Looking for a biochemistry analyser that delivers fast and reliable results for glucose, lactate and other metabolites? YSI, a Xylem brand, manufactures biochemistry analysers used across biotechnology, pharmaceutical development, cell culture, fermentation and food and beverage industries. We know lab, and we are here to help you choose the right YSI model for your application.
YSI biochemistry analysers are built on proprietary immobilised enzyme-electrode technology, delivering analyte-specific results in around 60 seconds. The instruments are user-friendly and robust, and maintenance is largely limited to membrane replacement and calibration checks.
What YSI biochemistry analysers measure
YSI instruments are designed for rapid, highly specific measurement of metabolites and ions. Available analytes include:
- Ammonium
- Choline
- Ethanol
- Galactose
- Glucose
- Glutamate
- Glutamine
- Glycerol
- Hydrogen peroxide
- Potassium
- Lactate
- Lactose
- Methanol
- Sucrose
- Xylose
The modular design lets you expand the analyte panel as your requirements evolve.
Each instrument can be ordered with a starter kit for the relevant analytes (for example glucose and lactate, glutamine and glutamate, or ammonium and potassium).
Benchtop analysers or online monitoring?
The YSI range covers two main ways of working. The benchtop analysers YSI 2500 and YSI 2900 suit labs where samples are analysed manually on the instrument as needed. If you require continuous monitoring directly from one or more bioreactors, the 2900M Online Monitor and Control System or the multi-channel solution 2940 and 2980 is the right choice.
Typical applications
YSI instruments are used widely across research and industry.
- Monitoring of cell-culture media for glucose and glutamine consumption
- Tracking of fermentation by-products such as glycerol and ethanol
- Verification of sugar profiles in blood, food and beverage processing
- Hydrogen peroxide level checks in cleaning validation
- Process development and quality control in pharmaceutical manufacturing
- Bioprocess control alongside bioreactors and fermenters
Service and maintenance
YSI biochemistry analysers are designed for minimal internal maintenance. The operator replaces membranes and checks calibrations on a regular basis. External maintenance is carried out by a certified service technician, typically after around 1,000 hours of operation, or every six to twelve months depending on usage. Berner Lab offers service agreements with annual maintenance visits including a PM kit.
Installation and training
On delivery, installation, installation testing and user training are handled by qualified and certified service technicians. For regulated environments, installation qualification (IQ) and operational qualification (OQ) are also available.
Frequently asked questions about YSI biochemistry analysers
How quickly do I get results with a YSI biochemistry analyser?
The instruments deliver analyte-specific results in around 60 seconds thanks to YSI’s proprietary immobilised enzyme-electrode technology.
Which YSI model suits my lab?
It depends on the analytes you need to measure, your sample volume, and whether you need bench analysis or continuous monitoring. YSI 2500 is suitable for glucose and lactate only, YSI 2900 offers a broader analyte panel, and for online monitoring from bioreactors the 2900M or the multi-channel monitors 2940 and 2980 are the right choice. Contact us and we will help you choose the right configuration.
Which sample types can be analysed?
The benchtop analysers handle samples from a range of holders, including 96-well plates and microcentrifuge tubes, which makes them flexible for both small sample volumes and higher throughput. The online monitors are connected directly to the bioreactor or fermenter for continuous measurement.
What does maintenance involve?
Internal maintenance is mainly membrane replacement and calibration checks. External service is typically recommended every six to twelve months, depending on usage. Berner Lab offers service agreements including a PM kit.
Can YSI instruments be used in GMP-regulated environments?
Yes. We offer installation with IQ and OQ qualification for regulated environments. Validation and ongoing qualification are handled according to your own process.
Contact Berner Lab for advice on YSI biochemistry analysers
