CrystalBreeder – next generation crystallization platform for solid state research

CrystalBreeder from Technobis is a versatile medium-throughput crystallization platform that lets you run up to 32 parallel experiments with working volumes as low as 0.1 ml. The platform provides real-time turbidity readings and enables complete crystallization screenings with as little as 1 mg of sample per experiment – ideal when material is limited and time to results is critical.

Technobis is a Dutch company specializing in crystallization and solubility research, with Crystal16 as a well-known flagship product. CrystalBreeder is their next generation system, taking early-phase crystallization and polymorph screening to a new level.

Key features for efficient crystallization

Up to 32 parallel reactors – Run a complete crystallization or polymorph screening overnight with unmatched throughput.

Minimal sample requirement – Less than 32 mg total sample is needed for a full screening, making the platform ideal for early development phases.

Real-time turbidity readings – Get instant insight into crystallization progress across all 32 reactors in parallel.

Controlled evaporation – New module enabling flexible and reproducible evaporation crystallization.

Flexible vapor diffusion – Perform vapor diffusion experiments under controlled conditions.

Multiple crystallization modes – Cooling, cooling evaporation, slurry, thermocycling, vapor diffusion, and layering techniques – all in one platform.

Reliable early-phase solubility data – Stop guessing when making formulation decisions – CrystalBreeder delivers solid data early in the process.

Applications

CrystalBreeder is ideal for laboratories in pharmaceutical development, fine chemistry, and materials research where early solid state screening, polymorph identification, and solubility studies are central tasks. The platform is especially valuable in early development phases where sample material is limited and decision-supporting data needs to be generated quickly.

Would you like to know more about CrystalBreeder?

Contact us at Berner Lab and we will help you find the right solution for your laboratory. We know lab – from pipettes to complete platforms for crystallization and solubility research.

Questions? Contact our product managers for more information about Technobis’s range of crystallization instruments.