Labfors 5 bioreactor from INFORS HT
Labfors 5 bioreactor from INFORS HT
Labfors 5 from INFORS HT is a flexible benchtop bioreactor for culture volumes of 0.5 to 13 L. Run up to six parallel units from one touchscreen. Configurable for microbial cultivation, cell culture and solid-substrate bioprocesses.
Looking for a flexible bioreactor that handles microbial cultivation, cell culture and solid-substrate processes alike? Labfors 5 from INFORS HT, supplier of bioreactors and fermenters is a high-end all-rounder benchtop bioreactor built for research, process development and scale-up. We know lab, and we are here to help you configure a system that fits your applications.
Labfors 5 covers culture volumes from 0.5 L up to 13 L total volume and can run as a single unit or as a parallel setup with up to six units controlled from one touchscreen. The modular design lets you tailor temperature control, gassing strategy and vessel accessories to your needs.
Key features
- Flexible, application-optimised configurations
- Splash-proof touchscreen with OPC server for local control or SCADA integration
- Up to six parallel units from a single touchscreen
- Top drive with mechanical seal or magnetic coupling
- Four pumps per vessel for feed, acid, base and anti-foam
- Removable pump heads that can be autoclaved with the vessel
- Up to 24 parameters per vessel with digital instrumentation
- Compact 465 x 465 mm footprint
Configurations for your applications
Labfors 5 is available in versions covering a wide range of microbial applications and bioprocesses with solid substrates. The top plate features Pg13.5 and 19 mm ports for sensors such as pH, pO2, anti-foam, optical density and redox.
Up to four gases (air, N2, O2 and CO2) can be used in almost any combination, fed either via a mass flow controller or a rotameter.
Temperature control to suit your process
Choose between two temperature control systems. A single-walled vessel with an electrical heater pad and cold finger provides gentle heating and cooling up to 95 °C. A double-walled glass vessel with water circulation gives full visibility of your culture and maximum heat transfer for rapid temperature changes up to 60 °C.
Typical applications
Labfors 5 is a versatile platform used across cultivation strategies and organism types.
- Bacteria such as E. coli and Pseudomonas
- Yeasts such as P. pastoris and Saccharomyces
- Fungi such as Aspergillus and Streptomyces
- Anaerobic cultivation and halophiles
- Process Analytical Technology (PAT)
- Process development, optimisation, scale-up and scale-down
Cultivation strategies include batch, fed-batch and continuous culture.
Technical data
- Total volume: 2 L, 3.6 L, 7.5 L, 10 L and 13 L
- Maximum expansion: six base units per touchscreen
- Sterilisation: autoclavable
- Temperature range: cooling water temperature + 5 °C up to 60 °C (water circulation) or 95 °C (heater pad)
- Stirrer speed: 10 to 1,500 rpm with direct top drive
- Standard parameters: speed, temperature, pH, pO2, anti-foam, gas mix and gas flow
- Dimensions (W x D x H): 465 x 465 x 900 mm
Upgrade when you need to
Labfors 5 can be upgraded even after commissioning. With LabCIP for automated cleaning and sterilisation you free up time for more experiments. With eve bioprocess platform software from INFORS HT you can plan, control and analyse your bioprocesses through a web-based platform.
Frequently asked questions about Labfors 5
Which culture volumes does Labfors 5 handle?
Labfors 5 handles total volumes from 2 L up to 13 L depending on vessel size. Working volumes start at 0.5 L and go up to 10 L.
Can I run several Labfors 5 in parallel?
Yes. Up to six units can be controlled from one touchscreen, which makes Labfors 5 well suited to parallel experiments and statistical studies.
Which organisms can be cultivated in Labfors 5?
The bioreactor is used for bacteria, yeasts and fungi, as well as aerobic and anaerobic microbial cultivation. Optional configurations support cell culture and bioprocesses with solid substrates.
What is the difference between Labfors 5 and Labfors 5 SSF?
Read more about Labfors 5 SSF, optimised for simultaneous saccharification and fermentation. The standard version of Labfors 5 is designed for microbial bioprocesses in liquid media.
Can Labfors 5 be used for GMP applications?
The weld-free construction makes Labfors 5 suitable for applications where GMP requirements apply. Validation and qualification are handled according to your own process.
Annika Garnås
